Pharmaceutical Multi-effect Distilled Water Machine

The multi-effect distilled water machine for pharmaceutical use is a key equipment in the pharmaceutical industry for producing high-purity water for injection. The following is a detailed introduction about it:

1. Working Principle:
- The multi-effect distilled water machine utilizes the thermal energy of steam and condensate for multiple evaporations and condensations. Fully preheated purified water enters the equipment and undergoes evaporation sequentially in multiple series-connected evaporators. Only the first-effect evaporator requires an external heat source (such as industrial steam) for heating, while subsequent evaporators use the steam generated by the previous effect as the heat source. During the evaporation process, impurities, microorganisms, etc., in the water are left in the remaining concentrated water, while the steam, after multiple evaporation-condensation cycles, produces high-purity distilled water in the final-effect evaporator.
2. Structural Components:
- Evaporator: This is the core component, typically consisting of multiple units, divided into a heating chamber and an evaporation chamber. The heating chamber is composed of the outer walls of multiple tubes and the tower core, used for heat transfer; the evaporation chamber consists of the inner walls of multiple tubes and the tower body, where water evaporates. The evaporation chamber is generally equipped with spiral plates to remove droplets from the steam and eliminate pyrogens.
- Preheater: Mostly shell-and-tube or U-tube heat exchangers. The first-effect preheater uses the condensate formed after industrial steam heats the feedwater in the first-effect evaporator to preheat the feedwater about to enter the evaporator; the remaining preheaters use the condensate formed after the produced pure steam heats the unevaporated feedwater from the previous effect in the evaporator to preheat the feedwater.
- Condenser: Typically a dual condenser, including a feedwater condenser and a cooling water condenser. The feedwater condenser both preheats the feedwater and cools the mixture of the remaining pure steam produced by the final effect and the distillate from the preheaters, turning it into distilled water; the cooling water condenser is used to adjust the water production temperature. The condenser is equipped with a 0.2μm sterilizing air filter to remove non-condensable gases and prevent external air from entering.
- Multi-stage water pump: Used to transport water and maintain water circulation in the system.
- Frame: Provides support and fixes the various components of the equipment.
- Control cabinet: Contains the control system for operating the equipment, monitoring, and adjusting parameters such as temperature, pressure, and flow rate.
3. Advantages and Features:
- Energy-efficient and high-performance: Through the multi-effect evaporation design, thermal energy is fully utilized, significantly reducing energy consumption. Compared to single-effect distilled water machines, multi-effect machines can greatly improve energy utilization and save operating costs.
- Excellent water quality: Effectively removes impurities, microorganisms, organic matter, heavy metals, etc., from the water, producing distilled water with high purity that meets the stringent requirements of the pharmaceutical industry for water for injection.
- Stable operation: The equipment has a rational structural design, high operational stability, and can run continuously for long periods, meeting the needs of large-scale production in pharmaceutical enterprises.
- High automation: Equipped with advanced control systems, it enables automated operation, reduces manual intervention, and improves production efficiency and operational accuracy.
4. Application Scenarios:
- Mainly used in the production of sterile preparations such as injections, eye drops, and oral liquids in pharmaceutical enterprises, providing high-quality water for injection.
- In cleaning processes during drug production, such as equipment cleaning and container cleaning, high-purity distilled water produced by multi-effect distilled water machines is also required to ensure cleaning effectiveness and drug quality.
5. Key Selection Points:
- Water production capacity and purity: Based on the different requirements of pharmaceutical processes for water quality and quantity, select equipment with appropriate production capacity and the ability to meet purity standards.
- Energy consumption: Consider the energy consumption of the equipment and choose models with lower energy consumption to reduce long-term operating costs.
- Stability: The equipment should have good stability and reliability, reducing the frequency of failures and minimizing maintenance costs and impact on production.
- Ease of use: Operation and maintenance should be simple and convenient, making it easy for operators to master and perform daily upkeep.